International Journal of Pharmaceutical and Phytopharmacological Research
ISSN (Print): 2250-1029
ISSN (Online): 2249-6084
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2024   Volume 14   Issue 2

Assessment of Anti-oxidant Herbal Cream Formulation for Sun Protection Factor (SPF) Efficacy
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  1. Department of Pharmaceutics, Crescent College of Pharmaceutical Sciences, Kannur, KUHS, Kerala, India.
  2. Department of Pharmaceutical Chemistry, Crescent College of Pharmaceutical Sciences, Kannur, Kerala, India.
Citation
Vancouver
Somasekharan Nair S, Kamalamma S. Assessment of Anti-oxidant Herbal Cream Formulation for Sun Protection Factor (SPF) Efficacy. Int J Pharm Phytopharmacol Res. 2024;14(2):6-11. https://doi.org/10.51847/jKEIBaniMX
APA
Somasekharan Nair, S., & Kamalamma, S. (2024). Assessment of Anti-oxidant Herbal Cream Formulation for Sun Protection Factor (SPF) Efficacy. International Journal of Pharmaceutical And Phytopharmacological Research, 14(2), 6-11. https://doi.org/10.51847/jKEIBaniMX
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Abstract

The primary aim of the study is to develop creams containing herbal extract and assess their effectiveness. The utilization of natural products is of great significance due to concerns regarding the toxicity and side effects associated with modern drugs. The objective of this research is to formulate sun protection creams that are cost-effective, non-toxic, and efficacious, and to ascertain if these formulations are as effective as those already on the market. The study on skin moisturization revealed high significance (p<0.001), while the In vitro occlusion study indicated that the formulation displayed a significant percentage of occlusion (p<0.01). The examination of the sun protection factor demonstrated that the formulation exhibited significant sun protection values (p<0.01) and was comparable to the marketed cream. Notably, the Formulation, incorporating gallic acid as a marker ingredient, displayed a considerable percentage occlusion and sun protection factor compared to the marketed formulation, confirming their ability to remain on the skin surface and safeguard against UV radiation. Stability assessments of the formulation by freeze-thaw testing showed no significant variation in the parameters. Additionally, the preservative efficacy study exhibited a significant reduction in bacterial colonies, with over 99.9% reduction within seven days, and over 90% reduction in fungal colonies within 28 days.

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