International Journal of Pharmaceutical and Phytopharmacological Research
ISSN (Print): 2250-1029
ISSN (Online): 2249-6084
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2026 Volume 16 - Issue 4

1.
Model the Therapeutic Microenvironment Before Optimizing the Natural Product Lead Across Oxygenation, Matrix Properties, Cellular Crosstalk, Metabolism, and Local Drug Exposure
Page: 1 - 9
Views: 71
Downloads: 20
Carlos Ramirez, Elena Torres, Pablo Ortega, Sofia Mendes
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2.
Excipient Compatibility as a Predictive Problem for Botanical Actives Across Chemical Stability, Interfacial Interactions, Processing Conditions, and Dosage-Form Performance
Page: 10 - 19
Views: 70
Downloads: 20
Elena Fedorova, Alexey Volkov, Irina Morozova, Dmitry Kuznetsov
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3.
Data-Driven Prediction of Pharmaceutical Solid Forms Across Polymorphism, Crystallization, Molecular Packing, Stability, and Developability Decisions
Page: 20 - 29
Views: 80
Downloads: 25
Laura Keller, Thomas Lehmann, Simon Brunner, Christoph Meier, David Thompson
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4.
Predicting Polymorph Risk Before Formulation Locks in a Natural Product Candidate Through Crystal Landscape Reasoning and Solid-State Uncertainty Assessment
Page: 30 - 39
Views: 77
Downloads: 26
David Thompson, Sarah Mitchell, Rachel Adams, James Brown, Michael Lee
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5.
Machine Learning Across the Amorphous Solid Dispersion Design Space for Predicting Miscibility, Stability, Drug Release, and Formulation Failure
Page: 40 - 49
Views: 81
Downloads: 30
Michael Roberts, Sarah Thompson, James Anderson, Robert Smith
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6.
Organoid Response Maps Can Bridge Natural Product Screening and Human Therapeutics by Preserving Tissue Architecture, Heterogeneity, and Patient-Specific Biology
Page: 50 - 59
Views: 83
Downloads: 30
Ravi Kumar, Neha Sharma, Aniket Deshmukh, Sanjay Kulkarni, Arjun Nair
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7.
Predictive Modeling of Pharmaceutical Nanocrystals from 2017 to 2026 Across Particle Engineering, Physical Stability, Dissolution, and Oral Performance
Page: 60 - 70
Views: 77
Downloads: 25
Pierre Dubois, Marc Lefevre, Claire Moreau, Julien Martin, Thomas Dupont
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8.
Choosing Co-Crystal Partners for Plant-Derived Drug Candidates Using Molecular Complementarity, Solid-State Interactions, Solubility Gain, and Developability Constraints
Page: 80 - 88
Views: 45
Downloads: 30
George Wilson, Chloe Bennett, Ethan Wright, Jack Turner
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9.
Plasma Concentration Is Not Enough for Phytochemical Lead Selection When Tissue Distribution, Unbound Exposure, and Site-of-Action Pharmacokinetics Determine Efficacy
Page: 89 - 98
Views: 59
Downloads: 29
Hassan Ali, Mariam Farooq, Usman Shah, Bilal Khan, Sana Malik
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10.
Formulation Models Should Predict Failure Modes Rather Than Only Optima When Designing Pharmaceutical Systems for Complex Natural Product Candidates
Page: 99 - 108
Views: 60
Downloads: 27
Marco De Luca, Giulia Ferraro, Antonio Russo, Elena Rossi
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11.
Protein Corona Effects Belong in the Design Loop for Nanocarried Phytochemicals Because Biological Identity Can Override the Intended Nanoparticle Surface
Page: 109 - 118
Views: 68
Downloads: 27
Aisha Bello, Zainab Sule, Ibrahim Musa, Grace Adeyemi, Ahmed Youssef
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12.
Oral Lymphatic Transport Is an Underused Design Space for Lipophilic Natural Products with Poor Aqueous Solubility and Extensive First-Pass Loss
Page: 119 - 128
Views: 74
Downloads: 27
Grace Collins, Oliver Evans, Noah Williams, Ethan Brooks
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13.
Organ-on-Chip Evidence Should Constrain Natural Product Pharmacology Models Through Dynamic Exposure, Tissue Interfaces, Multicellular Interactions, and Human-Relevant Physiology
Page: 129 - 138
Views: 70
Downloads: 29
Nokuthula Dlamini, Sipho Zulu, Thabo Nkosi, Lerato Molefe
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14.
Physics-Informed Learning for Dissolution and Precipitation of Poorly Soluble Phytochemicals Across Formulation Conditions, Gastrointestinal Environments, and Dynamic Exposure States
Page: 139 - 149
Views: 64
Downloads: 24
Fatima El Idrissi, Samira Bennani, Youssef Benali, Ahmed Ben Ali
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15.
Discovering Closed-Form Pharmacokinetic Relationships with Symbolic Regression to Improve Interpretability, Mechanistic Plausibility, and Extrapolation Beyond Black-Box Prediction
Page: 150 - 158
Views: 66
Downloads: 26
Nguyen Thanh Huy, Pham Quang Minh, Le Thi Bich, Tran Van Nam
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Volume 17
Issue 1
2027
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2026
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2025
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