International Journal of Pharmaceutical and Phytopharmacological Research
ISSN (Print): 2250-1029
ISSN (Online): 2249-6084
Publish with eIJPPR Submission
2023   Volume 13   Issue 2

Diuretic Activity of Ethanolic Extract of Bauhinia tomentosa Linn Roots
Download PDF


, ,
Citation
Vancouver
Bhat R, Shanbhag P, Shabaraya AR. Diuretic Activity of Ethanolic Extract of Bauhinia tomentosa Linn Roots. Int J Pharm Phytopharmacol Res. 2023;13(2):25-9. https://doi.org/10.51847/Aw0gV7Mqbh
APA
Bhat, R., Shanbhag, P., & Shabaraya, A. R. (2023). Diuretic Activity of Ethanolic Extract of Bauhinia tomentosa Linn Roots. International Journal of Pharmaceutical And Phytopharmacological Research, 13(2), 25-29. https://doi.org/10.51847/Aw0gV7Mqbh
Download citation:   EndNote   RIS
Article Link:
Downloads: 295
Views: 1145
Abstract

The present research examined the diuretic potential of the ethanolic derivatives of Bauhinia tomentosa  Linn roots. The roots of this plant have been traditionally used for their diuretic effects, but scientific evidence supporting this claim is limited. The study utilized Wistar rats and evaluated urine volume, electrolyte excretion, and renal function to assess the diuretic functionality of the derivative. The findings demonstrated that the ethanolic extract considerably uprises urine output and improved the excretion of Na, K, and Ch compared to the control group. The diuretic effect was dose-dependent, with higher doses producing a greater effect. Furthermore, the diuretic activity of the derivative was comparable to that of the standard diuretic drug, furosemide. Statistical analysis confirmed the significance of the findings (p < 0.001). The phytochemical composition of the extract, which includes flavonoids, alkaloids, tannins, saponins, and phenolic compounds, may contribute to its diuretic properties. The study suggests that Bauhinia tomentosa  Linn roots have potential as a natural diuretic agent, offering advantages over synthetic diuretics with fewer side effects. Further studies are needed to identify the active ingredient responsible for the observed diuretic effect and to elucidate the underlying mechanisms . The outcome is in line with  the locally use of Bauhinia tomentosa  Linn roots as a diuretic and warrant further investigation into their therapeutic applications.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

International Journal of Pharmaceutical and Phytopharmacological Research
Copyright © 2024 International Journal of Pharmaceutical and Phytopharmacological Research