Diuretic Activity of Ethanolic Extract of Bauhinia tomentosa Linn Roots

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The present research examined the diuretic potential of the ethanolic derivatives of Bauhinia tomentosa  Linn roots. The roots of this plant have been traditionally used for their diuretic effects, but scientific evidence supporting this claim is limited. The study utilized Wistar rats and evaluated urine volume, electrolyte excretion, and renal function to assess the diuretic functionality of the derivative. The findings demonstrated that the ethanolic extract considerably uprises urine output and improved the excretion of Na, K, and Ch compared to the control group. The diuretic effect was dose-dependent, with higher doses producing a greater effect. Furthermore, the diuretic activity of the derivative was comparable to that of the standard diuretic drug, furosemide. Statistical analysis confirmed the significance of the findings (p < 0.001). The phytochemical composition of the extract, which includes flavonoids, alkaloids, tannins, saponins, and phenolic compounds, may contribute to its diuretic properties. The study suggests that Bauhinia tomentosa  Linn roots have potential as a natural diuretic agent, offering advantages over synthetic diuretics with fewer side effects. Further studies are needed to identify the active ingredient responsible for the observed diuretic effect and to elucidate the underlying mechanisms . The outcome is in line with  the locally use of Bauhinia tomentosa  Linn roots as a diuretic and warrant further investigation into their therapeutic applications.