Background: Sickle cell disorder is commonly found in Saudi Arabia. There is no reliable information on the influence of sickle cell and the mortality rate of people aged five years and younger. Several types of research have deliberated the occurrence of SCD. The researches in the Middle East Arab Nations have established the presence of precise risk influences assembly SCD extra prevailing in this portion of the world.
Aim: To review results of previous studies regarding prevalence and complications of sickle cell disease among children in Saudi Arabia
Methodology: This is a systematic review, including PubMed, Google Scholar, and EBSCO that by examining randomized controlled trials, observational, and experimental studies investigates sickle cell disease among children in Saudi Arabia.
Results and Conclusion: The research included 8 studies and concluded that results show elevation of the frequency of sickle cell disease in Saudi Arabia especially in the eastern and southern districts of the kingdom. Proper vaccinations and blood transfusions aimed at children at risk of complications are advised. Neonatal screening programs for sickle cell disease should be considered. Selective screening of the children at risk or with a history of consanguinity between parents rather than universal screening is more appropriate.