International Journal of Pharmaceutical and Phytopharmacological Research
ISSN (Print): 2250-1029
ISSN (Online): 2249-6084
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2021   Volume 11   Issue 1

Role of Glucagon-like peptide-1 “Liraglutide” in Management of Type 1 Diabetes
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Abdulrahman Jameel A Sehly, Rayyan Fahad H Altemani, Yousef Hussain J Alharthi, Aminah Ghanem S Alhwiti, Abdulaziz Abdulrahman A Bedaiwi, Waad Maher Alqulayti, Rakan Ahmed I Alshuwaier, Abdulrahman Saleh A Alaql, Ibrahim Mahmoud H Ajwah
Citation
Sehly A J A, Altemani R F H, Alharthi Y H J, Alhwiti A G S, Bedaiwi A A A, Alqulayti W M et al. Role of Glucagon-like peptide-1 “Liraglutide” in Management of Type 1 Diabetes. Int j pharm phytopharm res 2021;11(1):89-93
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Abstract

Glucagon-like peptide-1 ‎(GLP-1) overpowers glucagon secretion, endorses satiety, postpones gastric draining, and arouses peripheral glucose consumption. This systematic review was carried out including PubMed, Google Scholar, and EBSCO that examined randomized controlled trials, observational, and experimental studies that had studied the role of GLP-1 (liraglutide) in controlling juvenile diabetes. The study included 7 studies and concluded that the introduction of liraglutide to insulin treatment juvenile diabetic patients results in a considerable and fast decrease in glycemic excursions and a consequent reduction in insulin dose. Body weight decreases substantially as reported in many studies.


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