TY  - JOUR
T1  - The Co-Crystal Approach: An Avenue for Improving Drug Bioavailability
A1  - Samarpan Sarangi
A1  - Simran Singh
A1  - Jigyasha Dhakal
A1  - Bunu Khatiwada
A1  - Arnab Das
A1  - Prithviraj Chakraborty
JF  - International Journal of Pharmaceutical And Phytopharmacological Research
JO  - Int J Pharm Phytopharmacol Res
SN  - 2250-1029
Y1  - 2023
VL  - 13
IS  - 1
DO  - 10.51847/yf34beVi2Y
SP  - 19
EP  - 32
N2  - The formulators' main concern when designing and developing a new pharmaceutical formulation is the poor water solubility and the permeability in the present scenario. These difficulties are most common in group III and IV medications, and they impact the bioavailability of dose forms. There are many methods for dealing with these problems, but they all have serious flaws, like the fact that they are all reliant on the physical and chemical makeup of the medication. To deal with issues like these, cocrystal is a simple and effective way to increase the solubility and permeability of a medicinal component without changing the drug's pharmacological effects. A drug's solubility, dissolving profile, pharmacokinetics, and stability can all be improved by cocrystallization with a conformer. This review article delivers a general impression of cocrystals like properties, method of preparation, evaluation, advantages, and uses. This review will also surely give a brief introduction to cocrystals. 
UR  - https://eijppr.com/article/the-co-crystal-approach-an-avenue-for-improving-drug-bioavailability-fxj2tbeoo4uxvm0
ER  -