TY  - JOUR
T1  - Standardizing Herbal Medicines with AI: Chemical Fingerprints, Bioactivity Profiles, Quality Markers, and Therapeutic Consistency
A1  - Mohamed Saif
A1  - Aisha Ahmed
A1  - Fatima Al-Mansoori
A1  - Khalid Al-Hassan
JF  - International Journal of Pharmaceutical And Phytopharmacological Research
JO  - Int J Pharm Phytopharmacol Res
SN  - 2250-1029
Y1  - 2025
VL  - 15
IS  - 5
DO  - 10.51847/2Ky305L24S
SP  - 63
EP  - 72
N2  - Herbal medicine standardization remains a major challenge because botanical identity, plant part, production context, processing method, extraction conditions, multi-constituent chemistry, biological relevance, and safety awareness all influence product quality. Chemical fingerprints can support identity confirmation, compositional comparison, and batch-level quality assessment, but chemical similarity alone cannot establish therapeutic consistency. Bioactivity profiles can add biological meaning to analytical patterns, yet they require assay relevance, reproducibility, and cautious interpretation. This article develops an original AI-assisted conceptual model for herbal medicine standardization that connects botanical authentication, processing context, chemical fingerprinting, metabolomic profiling, marker compound quantification, bioactivity profiling, quality-marker selection, batch consistency, anomaly detection, safety-marker screening, validation gates, and therapeutic consistency boundaries. The proposed model positions artificial intelligence as a decision-support layer for feature selection, pattern recognition, batch classification, chemical–bioactivity alignment, candidate quality-marker prioritization, and uncertainty communication. It does not present AI outputs, chemical fingerprints, or bioactivity patterns as validated product standards or clinical equivalence claims. The main contribution is a structured conceptual framework that clarifies how analytical, biological, computational, and interpretive evidence can be integrated while preserving the distinction between standardization hypotheses, validated quality markers, therapeutic relevance, and regulatory interpretation.
UR  - https://eijppr.com/article/standardizing-herbal-medicines-with-ai-chemical-fingerprints-bioactivity-profiles-quality-markers-ecmflo4qqhzjuup
ER  -