Cancer is the second leading cause of mortality worldwide. Unfortunately, despite appropriate and standard therapeutic approaches, they are often disappointing in long-term improving the prognosis and quality of life among patients. On the other hand, the integrated utilization of traditional and complementary medical approaches along with conventional treatments opens a hopeful horizon in front of our sights. Traditional Persian Medicine (TPM) considers the human body as a smart and intelligent organism, possessing significant capabilities to preserve the health and healing of the diseases. This trend of medicine, based on the fundamental concept of Midzaj (temperament) and every person’s unique features, has demonstrated six principles to have a healthy lifestyle and emphasis on the importance of preserving health on the title of “Setteh-e-zarurieah” which has provided health for people during centuries. The evidence suggested that it is inevitable to have healthy and personalized lifestyle along with conventional treatments to achieve the good health of any person.