This study was conducted to describe physical activity levels and motivators and barriers of university students in humanitarian and health colleges. A descriptive-analytical investigation was carried out on 335 students from the University of Ha'il, Saudi Arabia and included information about lifestyle patterns in terms of age, sex, BMI, study field and year of study. The results showed that university students exercise a little and the females of the health colleges are the lowest, but students of the normal weight exercise more than others, while there is a highly statistically significant difference with a P-value of ˂ 0.001 in favor of the physical activity when joining the university compared with the physical activity at university. Nagelkerke R2 revealed that almost one-third of the variance in the dependent variable of low physical activities could be explained by the 12 independent variables in the model. Knowledge deficit as a barrier; Low perception of physical health evaluation, low perception of a healthy diet and eating more than three times a day came out to predict low physical activity at a significant level less than 0.05.