TY  - JOUR
T1  - In-silico Molecular Docking, ADME and Drug Likeness Predictions of Some α-alkylidene-β-ethoxycarbonyl Cyclopentanones
A1  - Feten Beji
A1  - Reem al Harbi
A1  - Arshi Naqvi
JF  - International Journal of Pharmaceutical And Phytopharmacological Research
JO  - Int J Pharm Phytopharmacol Res
SN  - 2250-1029
Y1  - 2020
VL  - 10
IS  - 4
SP  - 126
EP  - 132
N2  - Computer-aided drug design (CADD) conception in the present-day scenario has transfigured the total drug discovery and development program. The pharmacodynamic and pharmacokinetic aspects of a drug candidate play a key role in deciding its fate as a therapeutic agent. The pharmacokinetic fortune of any drug candidate is determined by various properties like its absorption, distribution, metabolism, and elimination (ADME). In this report, an in-silico examination of α-alkylidene-β-ethoxycarbonyl cyclopentanones (1-7) was persuaded based on various physico-chemical parameters to predict their drug-likeness, pharmacokinetic and docking profile utilizing different computational tools. 
UR  - https://eijppr.com/article/in-silico-evaluations-of-some-methylene-butyrolactone-analogues
ER  -