The research pays more attention on evaluating the impact of patient education as directed by a clinical pharmacist concerning the disease, useful effects of treatment, causes of the disease, life style modifications and finally improving quality of life of patients diagnosed with Gastroesophageal reflux disease (GERD). It is a prospective observational study, GSRS scores according to baseline, follow up1 and follow up2 were 7.552 ± 3.63, 3.724 ± 3.39 and 1.414 ± 2.95 in mild (GERD A) patients. In moderate patient, scores were 11.042 ± 3.52, 5.792 ± 2.54 and 1.917 ± 3.01, in severe 10.154 ± 3.955, 6.462 ± 3.71 and 3.00 ± 4.51. HRQL scores of mild (GERD A) patient were 26.069± 12.77, 16.139± 12.19 and 8.138 ± 13.82 according to baseline, follow up1 and follow up2. Similarly moderate (GERD B) patient scores were 30.33±8.61, 17.918 ± 7.51 and 7.583 ± 8.40. Severe (GERD C) scores were 35.846 ± 12.07, 22.308 ± 8.17 and 8.923 ± 7.51. The significant reduction in GSRS scores shows developments in health related quality of life (HRQL) of GERD affected individuals. According to the results of this study, it shows that patient education can effectively reduce symptoms and improve the QOL of GERD patients.