TY  - JOUR
T1  - Evaluation of Relationship between Tissue Levels of Polycyclic Aromatic Hydrocarbon (PAHs) and History of Food Exposure to Environmental Contaminants in Patients with Gastric Cancer by Immunohistochemistry
A1  - Zahra Asadi
A1  - Sepideh Arbabi
JF  - International Journal of Pharmaceutical And Phytopharmacological Research
JO  - Int J Pharm Phytopharmacol Res
SN  - 2250-1029
Y1  - 2020
VL  - 10
IS  - 5
SP  - 210
EP  - 215
N2  - Gastric cancer is one of the most common cancers in the world and in the north and northwest of Iran. Given a high prevalence of polycyclic aromatic hydrocarbons (PAHs) in the environment as one of the influential factors in cancer, the present study was conducted to evaluate the relationship between tissue levels of polycyclic aromatic hydrocarbon (PAHs) and history of food exposure to environmental contaminants. Immunohistochemistry was performed in patients with gastric cancer. The study population included 30 patients with gastric cancer. Thirty tissue samples were randomly selected among patients with gastric cancer and a questionnaire was used to assess the role of environmental factors and nutritional factors in the incidence of gastric cancer. Patients' tissue blocks were examined by BPDE-5D11 monoclonal antibody to determine the tissue expression of PAH using immunohistochemistry (IHC). Statistical analysis of data was performed using SPSS16 software. The results showed that the tissue level of PAH is associated with factors such as the place of birth of patients (rural or urban), gender of patients (male and female), type of PAH expression (diffuse, focal), and smoking (p 
UR  - https://eijppr.com/article/evaluation-of-relationship-between-tissue-levels-of-polycyclic-aromatic-hydrocarbon-pahs-and-history-of-food-exposure-to-environmental-contaminants-in-patients-with-gastric-cancer-by-immunohi
ER  -