Background: Epilepsy is the most prevalent neurological condition and is one of the most prevalent non-infectious diseases in the world. It has been reported that epilepsy is the commonest disorder encountered in most pediatric neurology clinics in the developing world. Objective: Is to identify prevalence in different regions, causes, risk factors, and management of epilepsy among Saudi children. Method: This is a systematic review including PubMed, Google Scholar, and EBSCO that by examining randomized trials, uses the following terms in different combinations: epilepsy, prevalence, causes, risk factors, and treatment of epilepsy amongst Saudi children. Results: The review included 9 randomized studies that identified prevalence in different regions, causes, risk factors, and treatment of epilepsy amongst Saudi children. Conclusion: High prevalence of epilepsy in infants and children was observed in Saudi Arabia. Family History and consanguinity among parents are well-identified risk factors in KSA