TY - JOUR T1 - Effect of Saffron on Anti-Inflammatory and Oxidative Stress in Asthma A1 - Mehdi Bahraini A1 - Seyed Ahmad Hosseini A1 - Bahman Cheraghian A1 - Maryam Haddadzadeh Shoushtari JF - International Journal of Pharmaceutical And Phytopharmacological Research JO - Int J Pharm Phytopharmacol Res SN - 2250-1029 Y1 - 2020 VL - 10 IS - 5 SP - 179 EP - 184 N2 - Introduction: This trial was designed to evaluate the efficacy of saffron supplementation in patients with mild to moderate asthma. Methods: Settings and Design: This randomized, double-blind, and placebo-controlled trial was conducted on 72 patients with persistent allergic asthma.  Patients were assigned into take either 100 mg/day saffron supplement (intervention group) or a placebo capsule (control group) for eight weeks. The participants' anthropometric and biochemical evaluations were measured at the beginning and end of the study. Statistical analysis used: To analyse the data, the SPSS software version 24 was used. The continuous and categorical data were reported in means/standard deviations and frequency (%), respectively. Pre- and post-intervention measures were compared between groups using the paired t-test or the Mann-Whitney U-test for normal distributions. Results: At the end of the study, patients who received saffron had lower levels of pro-oxidant/antioxidant balance compared to the group who received placebo (P UR - https://eijppr.com/article/effect-of-saffron-on-anti-inflammatory-and-oxidative-stress-in-asthma ER -