Globally, breast cancer (BC) is the second most lethal cancer that affects women and in rare cases, men as well. More than 90% of breast cancer-associated deaths are caused due to late identification that leads to metastasis. Biopsy report along with imaging work-up (MRI- and CT-scans) predicts the diagnosis that ultimately uses for the establishment of treatment options. Currently, breast cancer treatment has broad and diverse approaches, it comprises conventional treatments which include oncoplastic breast surgery, radiation therapy, and adjuvant chemotherapy while advanced treatments include systemic therapy approaches including targeted therapy, hormone therapy, and immunotherapy. Advanced treatments aim to attack cancer cells specifically, reduce side effects and improve treatment outcomes for patients. The therapies can be further diverged and depend on taking the grounds of molecular subtypes of BC, patient health, and personal preferences along with regular screening. In this review, we have highlighted different therapeutic approaches including targeted therapy, chemotherapy, and hormonal therapy employed based on molecular subtypes of BC.