TY  - JOUR
T1  - Bacteriological Analysis with Antimicrobial Sensitivity and Resistance Pattern in Blood Culture of Septicemic Patient from Different Wards of a Tertiary Care Hospital in India ‎
A1  - Rohit Tiwari
A1  - Suraj Sandil
A1  - Parminder Nain
A1  - Jaspreet Kaur
JF  - International Journal of Pharmaceutical And Phytopharmacological Research
JO  - Int J Pharm Phytopharmacol Res
SN  - 2250-1029
Y1  - 2020
VL  - 10
IS  - 4
SP  - 112
EP  - 119
N2  - Background: Septicemia is one of the leading causes of morbidity and mortality in India where a large number of broad-spectrum antibiotics as empirical therapy implement against causative microorganism has led to the emergence of multidrug-resistant of these strains. Object: The present study was conducted to determine bacterial etiology with antibiotic susceptibility and resistance profile of isolated organisms from septicemia. Methods: This retrospective observational study was conducted over a period of six months to evaluate the blood culture, sensitivity, and resistance pattern of various antimicrobial agents used in septicemic patients. Results: We collected and analyzed a total of 380 blood culture reports during the study period of which 345 (90.78%) samples were found to be positive, out of which 62.02 % was found to be gram-positive bacteria whereas 37.98% was gram-negative bacteria. The most commonly isolated organisms were Staphylococcus aureus (83.28%), Micrococcus species (6%), Enterococcus species (6%), and Staphylococcus saprophyticus (5%) under gram-positive bacteria. The majority of organisms isolated were resistant to commonly used antibiotics like 2nd & 3rd generation cephalosporin, which showed more than 90% resistance for gram-positive and gram-negative organisms. Conclusion: The results obtained from this study showed aminoglycosides as a highly sensitive antibiotic and cephalosporin as a highly resistant antibiotic. This study would guide the clinicians to formulate appropriate treatment strategies as well as to take various preventive measures which ultimately would help to decrease sepsis-related mortality. 
UR  - https://eijppr.com/article/bacteriological-analysis-with-antimicrobial-sensitivity-and-resistance-pattern-in-blood-culture-of-septicemic-patient-from-different-wards-of-a-tertiary-care-hospital-in-india
ER  -