International Journal of Pharmaceutical and Phytopharmacological Research
ISSN (Print): 2250-1029
ISSN (Online): 2249-6084
Publish with eIJPPR Submission
2020   Volume 10   Issue 6

An Overview on Turner Syndrome: Literature Review
Download PDF


Fahad A. Mahdi, Munif E. Alanazi, Naif E. Alanazi, Salem A. Alhakami, Ibrahim A. H. Alazmi, Enad N. Almotairi, Mlouk B. T. Shabrawishi, Nasser A. W. Almutairi, Maha I. Alanazi, Hassan M. Alibrahim, Yasir J. R. Al-rashdi
Citation
Download citation:   EndNote   RIS
Article Link:
Abstract

Background: Aneuploidy is defined as the disturbance of the normal chromosomal amount. Normally, the human cell contains 46 chromosomes, however, in fetuses with aneuploidy, it might increase or decrease beyond the normal level. Turner syndrome is a complex genetic condition in which a female fetus suffers from a complete or partial loss if an X chromosome. Objectives: In this paper, we will review the available literature discussing the features, diagnosis, and management of Turner syndrome. Methodology: We conducted the literature search within the PubMed database using the keywords: “turner syndrome” and “X-monosomy” and “genetics” and “cognitive-behavioral” and “psychosocial” with dates from 1990 to 2020. Review: TS constitute a partially or completely loss of X-chromosome. Almost half of the patients with TS possess a non-mosaic karyotype. Among the most commonly reported physical feature of TS include decreased adult height, infertility, increase blood pressure, and micrognathia. Conclusion: In conclusion, TS is one of the most common chromosomal abnormalities that affect females. Early detection through characteristic physical and clinical features could have a massive impact on the function of affected individuals later in their lives.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

International Journal of Pharmaceutical and Phytopharmacological Research
© 2024 All rights reserved