%0 Journal Article
%T A Comparison of the Efficacy of Dexamethasone and Ketorolac in Preventing Postoperative Pain and Side-effects in Gynecologic Laparoscopic Surgeries: A Double-blind Randomized Clinical Trial
%A Zahra Asgari
%A Bahareh Meybodi
%A Masoumeh Nataj Majd
%A Reyhaneh Hosseini
%A Farahnaz Hajibeygi
%J International Journal of Pharmaceutical And Phytopharmacological Research
%@ 2250-1029
%D 2020
%V 10
%N 5
%P 226-231
%X Background: The impact of preoperative administration of dexamethasone and ketorolac on postoperative analgesia and side-effects of laparoscopic surgeries is acknowledged. However, the efficacy of dexamethasone versus ketorolac has not been compared in any earlier investigations, which was the main goal of this study.

Methods: In a randomized, double-blind placebo control study, 114 females who were elected for minor laparoscopic surgeries were randomly allocated into the three study groups: 30 mg preoperative intravenous ketorolac, 8 mg preoperative intravenous dexamethasone, and preoperative placebo (normal saline). Postoperative pain was evaluated at 1h, 6h, 12h, and 24h after the laparoscopy using the Visual Analog Scale (VAS) for pain. Postoperative opioid consumption and the occurrence of nausea and vomiting were also recorded. 

Results: Characteristic features of the study groups were similar. In comparison with the placebo group, postoperative pain over time and opioid consumption were significantly lower in the dexamethasone (p
%U https://eijppr.com/article/a-comparison-of-the-efficacy-of-dexamethasone-and-ketorolac-in-preventing-postoperative-pain-and-side-effects-in-gynecologic-laparoscopic-surgeries-a-double-blind-randomized-clinical-trial